How does dry AMD become geographic atrophy (GA)?
Dry AMD progresses to geographic atrophy when protein deposits called drusen build up under the macula, causing the cells there to deteriorate and die over time. As more and more macular cells die, areas of the macula begin to waste away (atrophy). These atrophied areas Show Full Answer
How does dry AMD become geographic atrophy (GA)?
Dry AMD progresses to geographic atrophy when protein deposits called drusen build up under the macula, causing the cells there to deteriorate and die over time. As more and more macular cells die, areas of the macula begin to waste away (atrophy). These atrophied areas create permanent blind spots and represent the advanced stage of dry AMD, which is called geographic atrophy.
Not everyone with dry AMD develops GA - about 30 percent of people with dry AMD progress to this advanced stage. The progression typically happens gradually over years, though the timeline varies from person to person. Why does vision blur after 3-5 weeks between Izervay injections?
Izervay (avacincaptad pegol) is designed to slow the progression of geographic atrophy, but it doesn't stop the disease completely. The medication's effect may wear off somewhat between injections, which could explain why vision becomes blurrier as the next injection approaches.
It's important for Margo to discuss this pattern with her retina specialist. The timing of vision changes could indicate:
- The natural progression of GA between treatments
- That the injection schedule might need adjustment
- Other changes in her condition that need evaluation
She should contact her eye doctor right away if she notices sudden vision changes, new blind spots, or if the blurriness is getting worse over time.
January 15
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