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Real members of myAMDteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 5
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myAMDteam

Are you receiving both Vabysmo and another injection for your geographic atrophy and wet AMD?

Yes, it's becoming more common for people with both geographic atrophy (advanced dry AMD) and wet AMD to receive two different types of injections. Here's why:

Vabysmo is an anti-VEGF medication that treats wet AMD by blocking Show Full Answer

Are you receiving both Vabysmo and another injection for your geographic atrophy and wet AMD?

Yes, it's becoming more common for people with both geographic atrophy (advanced dry AMD) and wet AMD to receive two different types of injections. Here's why:

Vabysmo is an anti-VEGF medication that treats wet AMD by blocking abnormal blood vessel growth and leakage beneath the macula. However, it doesn't address the geographic atrophy component of your condition.

Your doctor is likely suggesting adding a complement inhibitor injection - either Izervay or Syfovre - which specifically targets geographic atrophy. These medications work differently by blocking part of your immune system that contributes to cell death in the macula.

The treatment approach makes sense because:
- Wet and dry AMD develop through different mechanisms
- Each requires its own targeted therapy
- Complement inhibitors can help slow geographic atrophy progression
- Anti-VEGF drugs like Vabysmo manage the wet AMD component

You'll need injections every one to two months for the complement inhibitor, while Vabysmo is typically given every one to four months depending on your response.

It's worth discussing with your doctor the specific benefits, potential side effects, and injection schedule for combining these treatments. Some members have shared concerns about managing multiple injections, so understanding your personalized treatment plan can help you feel more prepared.

March 5

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