When your ophthalmologist looks at the back of your eye, they can spot many changes. Some are serious and require treatment, while others cause no symptoms. Optic disc drusen and age-related macular degeneration (AMD) are chronic (long-term) eye disorders that both involve drusen deposits, though in different parts of the eye.
Many people with optic disc drusen don’t have any symptoms. However, being diagnosed with optic disc drusen may raise your risk of developing vision changes and age-related macular degeneration.
In this article, we’ll cover what optic disc drusen are, their potential symptoms, and what the research shows about their relationship to AMD.
Optic disc drusen, also known as optic nerve head drusen, are deposits that develop in the optic disc at the back of the eye. The optic disc is where the optic nerve connects to the retina. Optic disc drusen are made up of fatty proteins and calcium.
Drusen deposits often harden and become easier to see with age. Researchers aren’t sure why drusen form in the optic disc. If you have optic disc drusen, an ophthalmologist may be able to see white or yellow clumps during an eye exam.
Optic disc drusen affect about 1 percent to 2 percent of people in the United States.
Optic disc drusen can develop in one or both eyes. Because they may not cause symptoms, you might not realize you have them until your ophthalmologist finds them during an eye exam.
About 87 percent of people with optic disc drusen experience some degree of visual field defects (a lost area of vision). Possible symptoms of optic disc drusen include:
There’s no treatment that removes optic disc drusen. Trying to remove the deposits won’t help. These deposits usually aren’t serious but may cause some peripheral vision loss over time. This loss in vision is usually mild and doesn’t need to be treated.
However, having optic disc drusen may raise the risk of other eye conditions.
Though optic drusen and AMD have some commonalities, they have many differences:
The conditions do share some risk factors and may have genetic links.
People who have optic disc drusen may be more likely to have AMD. A 2025 observational review found participants with optic disc drusen had around four times the odds of having AMD compared to those without optic disc drusen. However, the study authors acknowledged that this connection wasn’t statistically significant, so more research is needed.
Both optic disc drusen and AMD are more common in white females, according to Frontiers in Ophthalmology. Other common risk factors include:
People with a family history of AMD may be more likely to develop both AMD and optic disc drusen.
A 2025 review found that the majority of participants with both optic disc drusen and AMD had a family history of AMD. According to past research, only 20 percent of people with only AMD have a family history of the condition. This may indicate that the two conditions may share a genetic link.
Because the possible inherited genetic relationship isn’t well understood, more research is needed.
If you’ve been diagnosed with optic disc drusen, you might consider asking your eye doctor about being screened for AMD.
There are several AMD risk factors that can’t be changed, including:
Other factors for AMD include hypertension (high blood pressure) and high cholesterol.
Although there can be genetic factors to these health conditions, it may be possible to improve these risk factors with diet, exercise, and medical treatment.
Other steps you can take that may reduce your risk for AMD include:
On myAMDteam, people share their experiences with AMD, get advice, and find support from others who understand.
Have you experienced changes in your peripheral vision that might be a sign of optic disc drusen? Let others know in the comments below.
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